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EFHD1 Antibody

  • 货号：
    CSB-PA880107LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, PC-3 whole cell lysate, 293T whole cell lysate, A549 whole cell lysate
      All lanes: EFHD1 antibody at 3.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 27, 17 kDa
      Observed band size: 27 kDa
    • IHC image of CSB-PA880107LA01HU diluted at 1:500 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of A549 cells with CSB-PA880107LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) EFHD1 Polyclonal antibody
  • Uniprot No.：
    Q9BUP0
  • 基因名：
    EFHD1
  • 别名：
    4931430I01Rik antibody; AI452351 antibody; DKFZp781H0842; antibody; EF hand domain containing 1 antibody; EF hand domain family; member D1 antibody; EF-hand domain-containing protein 1 antibody; EF-hand domain-containing protein D1 antibody; EFHD1 antibody; EFHD1_HUMAN antibody; FLJ13612 antibody; MGC103094 antibody; Mitocalcin antibody; MST133 antibody; MSTP133 antibody; PP3051 antibody; RGD1559565 antibody; Swiprosin 2 antibody; Swiprosin-2 antibody; SWS2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human EF-hand domain-containing protein D1 protein (15-72AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，EFHD1 Antibody (CSB-PA880107LA01HU)，的标记方式是Non-conjugated。对于EFHD1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA880107LB01HU EFHD1 Antibody, HRP conjugated ELISA
    FITC CSB-PA880107LC01HU EFHD1 Antibody, FITC conjugated
    Biotin CSB-PA880107LD01HU EFHD1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production. May play a role in neuronal differentiation.
  • 基因功能参考文献：
    1. EFHD1 functions as a novel mitochondrial Ca(2+) sensor underlying Ca(2+)-dependent activation of mitoflashes PMID: 26975899
    2. detection of methylation of PPP1R3C alone or in combination with EFHD1 in plasma DNA showed high sensitivity and specificity in CRC detection, and may be useful detection method for CRC, especially for early-stage CRCs. PMID: 24861485
    3. Cloning of novel mouse genes associated with neuronal function, including Efhd1. PMID: 12270117
  • 亚细胞定位：
    Mitochondrion inner membrane.
  • 数据库链接：

    HGNC: 29556

    OMIM: 611617

    KEGG: hsa:80303

    STRING: 9606.ENSP00000264059

    UniGene: Hs.516769