EBFP Mouse Polyclonal Antibody
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货号:CSB-PA588045
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规格:¥1760
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其他:
产品详情
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Uniprot No.:Q9ULX5
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基因名:RNF112
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宿主:Mouse
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反应种属:N/A
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免疫原:The EBFP Mouse Polyclonal Antibody detects EBFP & EBFP Tag protein.
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克隆类型:Polyclonal
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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产品提供形式:Liquid
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应用范围:WB
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:2000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
靶点详情
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功能:E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density.
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亚细胞定位:Membrane; Multi-pass membrane protein. Membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Nucleus, nuclear body. Nucleus, nucleoplasm. Endosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse, postsynaptic density. Perikaryon. Cell projection, neuron projection.
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蛋白家族:TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
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组织特异性:Predominantly expressed in brain. Decreased expression in glioma brain tumors as compared to normal brains (at protein level).
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数据库链接:
HGNC: 12968
OMIM: 601237
KEGG: hsa:7732
STRING: 9606.ENSP00000454919
UniGene: Hs.189482
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