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EBF2 Antibody

  • 货号：
    CSB-PA884503LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA884503LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) EBF2 Polyclonal antibody
  • Uniprot No.：
    Q9HAK2
  • 基因名：
    EBF2
  • 别名：
    EBF2 antibody; COE2Transcription factor COE2 antibody; Early B-cell factor 2 antibody; EBF-2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transcription factor COE2 protein (53-254AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，EBF2 Antibody (CSB-PA884503LA01HU)，的标记方式是Non-conjugated。对于EBF2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA884503LB01HU EBF2 Antibody, HRP conjugated ELISA
    FITC CSB-PA884503LC01HU EBF2 Antibody, FITC conjugated
    Biotin CSB-PA884503LD01HU EBF2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
  • 基因功能参考文献：
    1. EBF2 gene variants can contribute to KD [ Kawasaki disease]in the Korean population. PMID: 29749135
    2. Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1, EBF2 and ADAMTS6. PMID: 26686553
    3. Blnc1 forms a ribonucleoprotein complex with transcription factor EBF2 to stimulate the thermogenic gene program. Further, Blnc1 itself is a target of EBF2, thereby forming a feedforward regulatory loop to drive adipogenesis toward thermogenic phenotype. PMID: 25002143
    4. EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. PMID: 19671856
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    COE family
  • 数据库链接：

    HGNC: 19090

    OMIM: 609934

    KEGG: hsa:64641

    STRING: 9606.ENSP00000430241

    UniGene: Hs.491292