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DZIP3 Antibody

  • 货号：
    CSB-PA080047
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q86Y13
  • 基因名：
    DZIP3
  • 别名：
    DZIP3 antibody; KIAA0675E3 ubiquitin-protein ligase DZIP3 antibody; EC 2.3.2.27 antibody; DAZ-interacting protein 3 antibody; RING-type E3 ubiquitin transferase DZIP3 antibody; RNA-binding ubiquitin ligase of 138 kDa antibody; hRUL138 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DZIP3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
  • 基因功能参考文献：
    1. By monoubiquitination of H2A at lysine 119, 2A-HUB mediates a selective repression of a specific set of chemokine genes in macrophages, critically modulating migratory responses to TLR activation. PMID: 18206970
  • 亚细胞定位：
    Cytoplasm.
  • 组织特异性：
    Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
  • 数据库链接：

    HGNC: 30938

    OMIM: 608672

    KEGG: hsa:9666

    STRING: 9606.ENSP00000355028

    UniGene: Hs.409210