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DUSP8 Antibody

  • 货号：
    CSB-PA953662
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA953662(DUSP8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA953662(DUSP8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q13202
  • 基因名：
  • 别名：
    C11orf81 antibody; Chromosome 11 open reading frame 81 antibody; Deubiquitinating enzyme 8 antibody; Dual Specificity Phosphatase 8 antibody; Dual specificity phosphatase M3/6 antibody; Dual specificity protein phosphatase 8 antibody; Dual specificity protein phosphatase hVH 5 antibody; Dual specificity protein phosphatase hVH-5 antibody; DUS8 antibody; DUS8_HUMAN antibody; DUSP8 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ42476 antibody; FLJ42958 antibody; H1 phosphatase vaccinia virus homolog antibody; H1 phosphatase; vaccinia virus; homolog of antibody; HB5 antibody; hUBPy antibody; HVH5 antibody; HVH8 antibody; M3/6; mouse; homolog of antibody; Neuronal tyrosine threonine phosphatase 1 antibody; Serine/threonine specific protein phosphatase antibody; Ubiquitin carboxyl terminal hydrolase 8 antibody; Ubiquitin specific processing protease 8 antibody; Ubiquitin thiolesterase 8 antibody; VH5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human DUSP8
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues.
  • 基因功能参考文献：
    1. The phosphorylation of the M3/6 phosphatase by JNK in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK activation. PMID: 22100391
    2. DUSP8 is genetically linked to alcohol dependence and was found on chromosome 11p15.5 PMID: 13129832
    3. Because this variant of hVH-5 lacked intronic sequences in its genomic structure, we suggest it might be a processed pseudogene of hVH-5. PMID: 15899389
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 组织特异性：
    Abundant in brain, heart and skeletal muscle.
  • 数据库链接：

    HGNC: 3074

    OMIM: 602038

    KEGG: hsa:1850

    STRING: 9606.ENSP00000329539

    UniGene: Hs.41688