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DSN1 Antibody

  • 货号：
    CSB-PA880969ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: DSN1 antibody at 3.09 μg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: MCF-7 whole cell lysate
      Lane 3: Mouse lung tissue
      Lane 4: Mouse gonadal tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 41, 33, 39, 28 kDa
      Observed band size: 41, 34, 23 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA880969ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DSN1 Polyclonal antibody
  • Uniprot No.：
    Q9H410
  • 基因名：
    DSN1
  • 别名：
    C20orf172 antibody; Chromosome 20 open reading frame 172 antibody; dJ469A13.2 antibody; DSN1 antibody; DSN1; MIND kinetochore complex component; homolog antibody; DSN1; MIND kinetochore complex component; homolog (S. cerevisiae) antibody; DSN1; MIS12 kinetochore complex component antibody; DSN1_HUMAN antibody; FLJ13346 antibody; hKNL-3 antibody; Kinetochore associated protein DSN1 antibody; Kinetochore associated protein DSN1 homolog antibody; Kinetochore null 3 homolog antibody; Kinetochore-associated protein DSN1 homolog antibody; KNL3 antibody; MGC32987 antibody; MIS13 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Kinetochore-associated protein DSN1 homolog protein (1-356AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
  • 基因功能参考文献：
    1. this report provides clear evidence that overexpression of the AURKA, SKA3, and DSN1 genes strongly correlates with the progression of colorectal adenomas to colorectal cancer PMID: 27329586
    2. HsMis13 phosphorylation by Aurora B is required for organizing a stable bi-oriented microtubule kinetochore attachment that is essential for faithful chromosome segregation in mitosis. PMID: 18640974
  • 亚细胞定位：
    Nucleus. Chromosome, centromere, kinetochore.
  • 数据库链接：

    HGNC: 16165

    OMIM: 609175

    KEGG: hsa:79980

    STRING: 9606.ENSP00000362850

    UniGene: Hs.632268