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DPPA2 Antibody

  • 货号：
    CSB-PA118910
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA118910(DPPA2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q7Z7J5
  • 基因名：
    DPPA2
  • 别名：
    DPPA2 antibody; PESCRG1Developmental pluripotency-associated protein 2 antibody; Pluripotent embryonic stem cell-related gene 1 protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Fusion protein of Human DPPA2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds to target gene promoters, including NKX2-5 and SYCE1, but not GATA4, and may be involved in the maintenance of the active epigenetic status of these genes.
  • 基因功能参考文献：
    1. High DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis PMID: 26745102
    2. results showed that DPPA2 expression was significantly correlated to the depth of tumor invasion and progression of tumor cells through advanced stages in colorectal cancer. PMID: 25497006
    3. A important role of HIWI and DPPA2 in tumorigenesis and also in lymph node metastasis of tumor cells. PMID: 24532429
    4. Differential expression of the embryo/cancer gene ECSA(DPPA2) in human preimplantation development. PMID: 18467432
    5. ECSA/DPPA2 is a promising target for antigen-specific immunotherapy in non-small cell lung cancers PMID: 18519755
    6. In normal tissues, PLAC1 expression was restricted to the placenta while DPPA2 expression was restricted to the placenta and testis. PMID: 19705800

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  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues.
  • 数据库链接：

    HGNC: 19197

    OMIM: 614445

    KEGG: hsa:151871

    STRING: 9606.ENSP00000417710

    UniGene: Hs.351113