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DNTTIP1 Antibody

  • 货号：
    CSB-PA007089LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA007089LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA007089LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DNTTIP1 Polyclonal antibody
  • Uniprot No.：
    Q9H147
  • 基因名：
    DNTTIP1
  • 别名：
    C20orf167 antibody; Deoxynucleotidyltransferase terminal interacting protein 1 antibody; Deoxynucleotidyltransferase terminal-interacting protein 1 antibody; dJ447F3.4 antibody; DNTTIP1 antibody; TdIF 1 antibody; TdIF1 antibody; TDIF1_HUMAN antibody; TdT binding protein antibody; TdT interacting factor 1 antibody; TdT-interacting factor 1 antibody; Terminal deoxynucleotidyltransferase interacting factor 1 antibody; Terminal deoxynucleotidyltransferase-interacting factor 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Deoxynucleotidyltransferase terminal-interacting protein 1 protein (1-329AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DNTTIP1 Antibody (CSB-PA007089LA01HU)，的标记方式是Non-conjugated。对于DNTTIP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA007089LB01HU DNTTIP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA007089LC01HU DNTTIP1 Antibody, FITC conjugated
    Biotin CSB-PA007089LD01HU DNTTIP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
  • 基因功能参考文献：
    1. In luciferase assays, TdIF1 can up-regulate transcription activity of the promoters containing the TdIF1-binding sequences, and this effect is mainly through the palindrome 5'-TGCATG-3'. PMID: 25619743
    2. During cell division, DNTTIP1 is part of the mitotic deacetylase complex MIDAC, which also contains C14ORF43/MIDEAS and HDAC1/HDAC2. PMID: 21258344
    3. During cell division, DNTTIP1 forms a complex with C14ORF43/MIDEAS and HDAC1/HDAC2. PMID: 21258344
    4. The TdT binding, DNA binding and dimerization regions, and nuclear localization signal (NLS) in TdIF1, were identified. PMID: 17663723
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 16160

    OMIM: 611388

    KEGG: hsa:116092

    STRING: 9606.ENSP00000361705

    UniGene: Hs.472852