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DLGAP3 Antibody

  • 中文名称：
    DLGAP3兔多克隆抗体
  • 货号：
    CSB-PA006942GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O95886
  • 基因名：
    DLGAP3
  • 别名：
    DLGAP3 antibody; DAP3Disks large-associated protein 3 antibody; DAP-3 antibody; PSD-95/SAP90-binding protein 3 antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human DLGAP3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
  • 基因功能参考文献：
    1. several rare variants of the DLGAP3 gene were found in this study which may be associated with schizophrenia. PMID: 23414653
    2. This study provides suggestive evidence that DLGAP3 and its interactive effect with SLC1A1 might be involved in susceptibility to developing OC symptoms in schizophrenia patients receiving AAP treatment. PMID: 21990008
    3. This study generated preliminary evidence to link SAPAP3 variants to the development of earlier onset obsessive-compulsive disorder. PMID: 21295225
    4. DLGAP3 remains a promising candidate gene for Tourette Syndrome. PMID: 21184590
    5. Sapap3 is a promising functional candidate gene for human grooming disorder (obsessive compulsive disorder). PMID: 19051237
    6. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. PMID: 19096451

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  • 亚细胞定位：
    Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
  • 蛋白家族：
    SAPAP family
  • 数据库链接：

    HGNC: 30368

    OMIM: 611413

    KEGG: hsa:58512

    STRING: 9606.ENSP00000235180

    UniGene: Hs.733945