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DEUP1 Antibody

  • 货号：
    CSB-PA004729LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA004729LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DEUP1 Polyclonal antibody
  • Uniprot No.：
    Q05D60
  • 基因名：
    DEUP1
  • 别名：
    DEUP1 antibody; CCDC67 antibody; Deuterosome assembly protein 1 antibody; Coiled-coil domain-containing protein 67 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Deuterosome assembly protein 1 protein (217-292AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DEUP1 Antibody (CSB-PA004729LA01HU)，的标记方式是Non-conjugated。对于DEUP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA004729LB01HU DEUP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA004729LC01HU DEUP1 Antibody, FITC conjugated
    Biotin CSB-PA004729LD01HU DEUP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.
  • 基因功能参考文献：
    1. Single nucleotide polymorphism in CCDC67 gene is associated with Acute Renal Graft Rejection. PMID: 27272414
    2. Loss of CCDC67 is associated with papillary thyroid carcinoma. PMID: 26716505
    3. suggest that CCDC67 is a putative tumor suppressor gene that is silenced in gastric cancers by promoter CpG methylation and that it may play an important role in cell signaling and migration related to tumorigenesis PMID: 22610074
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    CEP63 family
  • 数据库链接：

    HGNC: 26344

    KEGG: hsa:159989

    STRING: 9606.ENSP00000298050

    UniGene: Hs.436625