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DDX46 Antibody

  • 中文名称：
    DDX46兔多克隆抗体
  • 货号：
    CSB-PA006627GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q7L014
  • 基因名：
    DDX46
  • 别名：
    DDX46 antibody; KIAA0801Probable ATP-dependent RNA helicase DDX46 antibody; EC 3.6.4.13 antibody; DEAD box protein 46 antibody; PRP5 homolog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human DDX46
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays an essential role in splicing, either prior to, or during splicing A complex formation.
  • 基因功能参考文献：
    1. Knockdown of DDX46 inhibited osteosarcoma cell proliferation. PMID: 27697093
    2. DDX46 is critical for ESCC cells proliferation. PMID: 27176873
    3. DDX46 is critical for colorectal cancer (CRC) cell proliferation and is a potential therapeutic target for CRC treatment. PMID: 25680556
    4. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: DDX46. PMID: 19902070
    5. characterization of protein associated with the human 17S U2 snRNP and one of its stable subunits, SF3b; results indicate that Prp5 plays an important role in pre-mRNA splicing, acting during or prior to prespliceosome assembly PMID: 12234937
    6. Prp5 forms a bridge between U1 and U2 Small Nuclear Ribonucleoproteins at the time of pre-spliceosome formation PMID: 14713954

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  • 亚细胞定位：
    Nucleus speckle. Nucleus, Cajal body. Membrane; Lipid-anchor. Note=Present in Cajal bodies (CBs) and nuclear speckles.
  • 蛋白家族：
    DEAD box helicase family, DDX46/PRP5 subfamily
  • 数据库链接：

    HGNC: 18681

    OMIM: 617848

    KEGG: hsa:9879

    STRING: 9606.ENSP00000346236

    UniGene: Hs.406549