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DDX24 Antibody

  • 货号：
    CSB-PA040035
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q9GZR7
  • 基因名：
    DDX24
  • 别名：
    ATP dependent RNA helicase DDX24 antibody; ATP-dependent RNA helicase ddx24 antibody; DDX 24 antibody; ddx24 antibody; DDX24_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 24 antibody; DEAD box protein 24 antibody; DEAD/H (Asp Glu Ala Asp) box polypeptide 24 antibody; S. cerevisiae CHL1 like helicase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human DDX24.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    ATP-dependent RNA helicase.
  • 基因功能参考文献：
    1. DDX24 is a negative regulator of p53 transcriptional activity.DDX24 inhibits p300 mediated acetylation of p53. PMID: 25867071
    2. depletion of DDX24 in cells impaired pre-rRNA processing and resulted both in abrogation of MDM2 function and in consequent p53 stabilization PMID: 24980433
    3. knockdown of a DEAD-box protein named DDX24 inhibits the packaging of HIV-1 RNA and thus diminishes viral infectivity. PMID: 18289627
  • 蛋白家族：
    DEAD box helicase family, DDX24/MAK5 subfamily
  • 组织特异性：
    Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine.
  • 数据库链接：

    HGNC: 13266

    OMIM: 606181

    KEGG: hsa:57062

    STRING: 9606.ENSP00000328690

    UniGene: Hs.510328