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DCAF8 Antibody

  • 货号：
    CSB-PA725896HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse heart tissue, Mouse lung tissue
      All lanes: DCAF8 antibody at 3.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 67, 31 kDa
      Observed band size: 67 kDa
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA725896HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA725896HA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DCAF8 Polyclonal antibody
  • Uniprot No.：
    Q5TAQ9
  • 基因名：
    DCAF8
  • 别名：
    DCAF8 antibody; H326 antibody; WDR42ADDB1- and CUL4-associated factor 8 antibody; WD repeat-containing protein 42A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human DDB1- and CUL4-associated factor 8 protein (1-135AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DCAF8 Antibody (CSB-PA725896HA01HU)，的标记方式是Non-conjugated。对于DCAF8 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA725896HB01HU DCAF8 Antibody, HRP conjugated ELISA
    FITC CSB-PA725896HC01HU DCAF8 Antibody, FITC conjugated
    Biotin CSB-PA725896HD01HU DCAF8 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:2000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • 基因功能参考文献：
    1. DCAF8 p.R317C mutation is responsible for specific variety of HMSN2 with infrequent giant axons and mild cardiomyopathy. PMID: 24500646
    2. WDR42A is a nucleocytoplasmic shuttling protein. PMID: 22500989
    3. while RNF10 and WDR42A or VP22 alone showed distinct subcellular localization patterns, RNF10 and WDR42A were relocated when co-expressed with VP22 or its homologues; these potential host cell factors of VP22 might expand the list of host targets of VP22 PMID: 21424732
  • 相关疾病：
    Giant axonal neuropathy 2, autosomal dominant (GAN2)
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    WD repeat DCAF8 family
  • 数据库链接：

    HGNC: 24891

    OMIM: 610100

    KEGG: hsa:50717

    STRING: 9606.ENSP00000451235

    UniGene: Hs.632447