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Cytotoxin 4 Antibody

  • 货号：
    CSB-PA355645LA01NFG
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Naja atra N/A Polyclonal antibody
  • Uniprot No.：
    P01443
  • 基因名：
    N/A
  • 别名：
    antibody; Cytotoxin 4 antibody; CTX-4M antibody; CTX4 antibody; Cardiotoxin A4 antibody; CTX A4 antibody; Cardiotoxin analog IV antibody; CTX IV antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Naja atra
  • 免疫原：
    Recombinant Naja atra Cytotoxin 4 protein (22-81AA)
  • 免疫原种属：
    Naja atra
  • 标记方式：
    Non-conjugated

    本页面中的产品，Cytotoxin 4 Antibody (CSB-PA355645LA01NFG)，的标记方式是Non-conjugated。对于Cytotoxin 4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA355645LB01NFG Cytotoxin 4 Antibody, HRP conjugated ELISA
    FITC CSB-PA355645LC01NFG Cytotoxin 4 Antibody, FITC conjugated
    Biotin CSB-PA355645LD01NFG Cytotoxin 4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation.
  • 亚细胞定位：
    Secreted. Target cell membrane.
  • 蛋白家族：
    Snake three-finger toxin family, Short-chain subfamily, Type IA cytotoxin sub-subfamily
  • 组织特异性：
    Expressed by the venom gland.