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CYP3A7 Antibody

  • 货号：
    CSB-PA007546
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293T cells using CYP3A7 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P24462
  • 基因名：
    CYP3A7
  • 别名：
    Aryl hydrocarbon hydroxylase antibody; CP37 antibody; CP3A7_HUMAN antibody; CYP3A7 antibody; CYPIIIA7 antibody; Cytochrome P450 3A7 antibody; Cytochrome P450; family 3; subfamily A; polypeptide 7 antibody; Cytochrome P450; subfamily IIIA; polypeptide 7 antibody; Cytochrome P450-HFLA antibody; Flavoprotein linked monooxygenase antibody; Flavoprotein-linked monooxygenase antibody; Microsomal monooxygenase antibody; P 450(HFL33) antibody; P 450111A7 antibody; P450 HFLA antibody; Xenobiotic monooxygenase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CYP3A7.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    A cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Metabolizes 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone, DHEA), a precursor in the biosynthesis of androgen and estrogen steroid hormones. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1), particularly D-ring hydroxylated estrone at the C16-alpha position. Mainly hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may play a role in atRA clearance during fetal development. Also involved in the oxidative metabolism of xenobiotics including anticonvulsants.
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 组织特异性：
    Expressed in fetal liver (at protein level).
  • 数据库链接：

    HGNC: 2640

    OMIM: 605340

    KEGG: hsa:100861540

    STRING: 9606.ENSP00000337450

    UniGene: Hs.111944