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CSRP2 Antibody

  • 货号：
    CSB-PA880995DSR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CSRP2 antibody at 5.74μg/ml
      Lane 1: Mouse lung tissue
      Lane 2: A375 whole cell lysate
      Lane 3: A549 whole cell lysate
      Lane 4: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 21 kDa
      Observed band size: 21 kDa
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA880995DSR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CSRP2 Polyclonal antibody
  • Uniprot No.：
    Q16527
  • 基因名：
    CSRP2
  • 别名：
    CRP2 antibody; CSRP2 antibody; CSRP2_HUMAN antibody; Cysteine and glycine rich protein 2 antibody; Cysteine and glycine-rich protein 2 antibody; Cysteine rich protein 2 antibody; Cysteine-rich protein 2 antibody; LIM domain only protein 5 antibody; LMO-5 antibody; LMO5 antibody; SmLIM antibody; Smooth muscle cell LIM protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Cysteine and glycine-rich protein 2 protein (1-193AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
  • 基因功能参考文献：
    1. CSRP2 promoted cell proliferation, cell-cycle progression, in vitro colony formation and cell migration ability. Abnormal CSRP2 expression was associated with resistance to chemotherapy; sensitivity was restored by down-regulating CSRP2 expression. PMID: 28415593
    2. the effect of proteasome inhibition on IL-10 activation of the IL-10E1 pathway [Il-10E1] PMID: 12861049
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Highly expressed in the aorta, but not in heart and skeletal muscle.
  • 数据库链接：

    HGNC: 2470

    OMIM: 601871

    KEGG: hsa:1466

    STRING: 9606.ENSP00000310901

    UniGene: Hs.530904