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CSNK1G1 Antibody

  • 货号：
    CSB-PA001226
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COS7 cells using Casein Kinase Iγ1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9HCP0
  • 基因名：
  • 别名：
    9130020E21Rik antibody; Casein kinase 1 gamma 1 antibody; Casein kinase I isoform gamma 1 antibody; Casein kinase I isoform gamma-1 antibody; CKI gamma 1 antibody; CKI-gamma 1 antibody; CSNK1G1 antibody; EC 2.7.11.1 antibody; KC1G1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat,Monkey
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Casein Kinase Iγ1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Phosphorylates CLSPN.
  • 基因功能参考文献：
    1. CK1gamma1 phosphorylates p65 and consequently promotes its degradation by ubiquitin E3 ligases CUL2 and COMMD1. PMID: 24442433
    2. casein kinase 1 gamma 1 phosphorylates claspin PMID: 21680713
    3. A 1756 bp cDNA encoded human protein kinase CK1 (438 AA, mol wt 50.272 Da, isoelectric point of 9.37) mapping to chromosome 15q22. PMID: 12119564
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
  • 数据库链接：

    HGNC: 2454

    OMIM: 606274

    KEGG: hsa:53944

    STRING: 9606.ENSP00000305777

    UniGene: Hs.646508