Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. CRYAA Antibody

CRYAA Antibody

  • 货号：
    CSB-PA006007LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA006007LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CRYAA Polyclonal antibody
  • Uniprot No.：
    P02489
  • 基因名：
    CRYAA
  • 别名：
    Acry 1 antibody; Alpha crystallin A chain antibody; Alpha-crystallin A chain antibody; CRYA 1 antibody; CRYA1 antibody; CRYAA antibody; CRYAA_HUMAN antibody; Crystallin alpha 1 antibody; Crystallin alpha A antibody; Heat shock protein beta 4 antibody; Heat shock protein beta-4 antibody; HSPB 4 antibody; HspB4 antibody; short form antibody; Zonular Central Nuclear Cataract antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Alpha-crystallin A chain protein (98-173AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CRYAA Antibody (CSB-PA006007LA01HU)，的标记方式是Non-conjugated。对于CRYAA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA006007LB01HU CRYAA Antibody, HRP conjugated ELISA
    FITC CSB-PA006007LC01HU CRYAA Antibody, FITC conjugated
    Biotin CSB-PA006007LD01HU CRYAA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Contributes to the transparency and refractive index of the lens. In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
  • 基因功能参考文献：
    1. CRISPR/Cas9-mediated mutation of the alphaA-crystallin gene in rabbits recapitulates phenotypes of congenital cataracts, microphthalmia, obscurity, and early atrophy of the lens, and failed differentiation of lens fibers. PMID: 28475701
  • 相关疾病：
    Cataract 9, multiple types (CTRCT9)
  • 亚细胞定位：
    Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • 蛋白家族：
    Small heat shock protein (HSP20) family
  • 组织特异性：
    Expressed in the eye lens (at protein level).
  • 数据库链接：

    HGNC: 2388

    OMIM: 123580

    KEGG: hsa:102724652

    STRING: 9606.ENSP00000291554

    UniGene: Hs.184085