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CRIP1 Antibody

  • 货号：
    CSB-PA005969DSR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CRIP1 antibody at 1.44µg/ml + PC-3 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 9 kDa
      Observed band size: 9 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005969DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005969DSR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CRIP1 Polyclonal antibody
  • Uniprot No.：
    P50238
  • 基因名：
    CRIP1
  • 别名：
    CRHP antibody; CRIP antibody; CRIP1 antibody; CRIP1_HUMAN antibody; CRP-1 antibody; CRP1 antibody; Cysteine rich heart protein antibody; Cysteine rich intestinal protein antibody; Cysteine rich protein 1 (intestinal) antibody; Cysteine rich protein 1 antibody; Cysteine-rich heart protein antibody; Cysteine-rich intestinal protein antibody; Cysteine-rich protein 1 antibody; FLJ40971 antibody; hCRHP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Cysteine-rich protein 1 protein (1-77AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein.
  • 基因功能参考文献：
    1. CRIP1 promotes cell migration and invasion, mediates epithelial-mesenchymal transition, and activates the Wnt/betacatenin signaling pathway in cervical cancer PMID: 29959029
    2. CRIP1 acts as an oncogene in the cell proliferation, migration, and invasion processes of thyroid carcinoma. CRIP1 may serve well as an independent prognostic marker with significant predictive power for use in thyroid carcinoma therapy. PMID: 29059670
    3. The CRIP1 expression level was highest in the highly metastatic colon cancer cell lines and CRIP1 silencing did not significantly affect the percentage of apoptotic SW620 and HT29 cells. PMID: 29179181
    4. CRIP1 gene expression was correlated to measures of cardiac hypertrophy in Hypertension patients. Assessment of circulating CRIP1 (cystein-rich protein 1) levels as biomarkers showed a strong association with increased risk for incident stroke. PMID: 28784648
    5. This study provides evidence for a prognostic clinical potential of the combined study of GAL-3 and CRIP-1 in endometrial cancer PMID: 26708131
    6. CRIP1 expression is associated with long-term survival and no metastases in osteosarcoma patients. PMID: 22202598

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  • 数据库链接：

    HGNC: 2360

    OMIM: 123875

    KEGG: hsa:1396

    STRING: 9606.ENSP00000455329

    UniGene: Hs.70327