Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. CRHR1 Antibody

CRHR1 Antibody

  • 货号：
    CSB-PA005965EA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CRHR1 antibody at 16µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 51, 48, 44, 47, 29 kDa
      Observed band size: 51 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005965EA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA005965EA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA005965EA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CRHR1 Polyclonal antibody
  • Uniprot No.：
    P34998
  • 基因名：
  • 别名：
    Corticotropin releasing factor type 1 receptor antibody; corticotropin releasing hormone receptor 1 antibody; Corticotropin-releasing factor receptor 1 antibody; Corticotropin-releasing hormone receptor 1 antibody; CRF R antibody; crf receptor 1 antibody; crf receptor type 1 antibody; crf type 1 antibody; CRF-R antibody; CRF-R-1 antibody; CRF-R1 antibody; CRF1 antibody; CRFR antibody; CRFR-1 antibody; CRFR1 antibody; CRFR1_HUMAN antibody; CRH-R-1 antibody; CRH-R1 antibody; CRH-R1h antibody; CRHR antibody; Crhr1 antibody; CRHR1f antibody; CRHR1L antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Corticotropin-releasing factor receptor 1 protein (24-121AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CRHR1 Antibody (CSB-PA005965EA01HU)，的标记方式是Non-conjugated。对于CRHR1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005965EB01HU CRHR1 Antibody, HRP conjugated ELISA
    FITC CSB-PA005965EC01HU CRHR1 Antibody, FITC conjugated
    Biotin CSB-PA005965ED01HU CRHR1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Endosome. Note=Agonist-binding promotes endocytosis.
  • 蛋白家族：
    G-protein coupled receptor 2 family
  • 组织特异性：
    Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
  • 数据库链接：

    HGNC: 2357

    OMIM: 122561

    KEGG: hsa:104909134

    STRING: 9606.ENSP00000381333

    UniGene: Hs.417628