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CPO Antibody

  • 货号：
    CSB-PA005909LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA005909LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CPO Polyclonal antibody
  • Uniprot No.：
    Q8IVL8
  • 基因名：
    CPO
  • 别名：
    Carboxypeptidase O antibody; CBPO_HUMAN antibody; CPO antibody; Metallocarboxypeptidase C antibody; Metallocarboxypeptidase O antibody; MGC138281 antibody; MGC138283 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Carboxypeptidase O protein (21-101AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CPO Antibody (CSB-PA005909LA01HU)，的标记方式是Non-conjugated。对于CPO Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005909LB01HU CPO Antibody, HRP conjugated ELISA
    FITC CSB-PA005909LC01HU CPO Antibody, FITC conjugated
    Biotin CSB-PA005909LD01HU CPO Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins. Can also cleave C-terminal hydrophobic amino acids, with a preference for small residues over large residues.
  • 基因功能参考文献：
    1. hCPO can also trim C-t extensions of proteins, such as epidermal growth factor, suggesting a role in the maturation and degradation of growth factors and bioactive peptides. PMID: 29636417
    2. CPO cleaves acidic amino acids from dietary proteins and peptides, thus complementing the actions of well known digestive carboxypeptidases CPA and CPB. PMID: 21921028
  • 亚细胞定位：
    Apical cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Peptidase M14 family
  • 组织特异性：
    Detected in enterocytes of the ileum.
  • 数据库链接：

    HGNC: 21011

    OMIM: 609563

    KEGG: hsa:130749

    STRING: 9606.ENSP00000272852

    UniGene: Hs.684103