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CPNE3 Antibody

  • 货号：
    CSB-PA005902GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O75131
  • 基因名：
    CPNE3
  • 别名：
    Copine 3 antibody; Copine III antibody; Copine-3 antibody; Copine3 antibody; CopineIII antibody; CPN3 antibody; CPNE 3 antibody; CPNE3 antibody; CPNE3_HUMAN antibody; KIAA0636 antibody; PRO1071 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human CPNE3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation.
  • 基因功能参考文献：
    1. CPNE3(high) is an adverse prognostic biomarker for acute myeloid leukemia. PMID: 28670859
    2. Copine3 binding to ErbB2 increases when Jab1 is overexpressed in SKBr3 breast cancer cells. Copine3 and Jab1 binding regulates the ErbB2 signaling pathway. PMID: 26719032
    3. our results indicate that CPNE3 could play a critical role in NSCLC metastasis. PMID: 23713811
    4. This study demonistrated that dysregulation of cpne3 3'UTR in brain of patient with schizophrenia. PMID: 23062752
    5. Data suggest that Copine-III is a novel player in the regulation of ErbB2-dependent cancer cell motility. PMID: 20010870
    6. Susceptibility genes CPNE3, IL16 and CDH13 with moderate effects associated with susceptibility to prostate cancer. PMID: 18264096

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  • 亚细胞定位：
    Nucleus. Cytoplasm. Cell membrane. Cell junction. Cell junction, focal adhesion.
  • 蛋白家族：
    Copine family
  • 组织特异性：
    Expressed in breast and weakly in prostate and ovarian tissues. Expressed in neutrophils (at protein level). Widely expressed. Expressed in the brain. Expressed in neutrophil precursors from the bone marrow and peripheral blood. Expressed in primary breas
  • 数据库链接：

    HGNC: 2316

    OMIM: 604207

    KEGG: hsa:8895

    STRING: 9606.ENSP00000198765

    UniGene: Hs.191219