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CPA2 Antibody

  • 货号：
    CSB-PA561433
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA561433(CPA2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA561433(CPA2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse pancreas tissue, Primary antibody: CSB-PA561433(CPA2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P48052
  • 基因名：
    CPA2
  • 别名：
    CPA2Carboxypeptidase A2 antibody; EC 3.4.17.15 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human CPA2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. This study showed that CPA2 and CPB1 variants are not associated with chronic pancreatitis. PMID: 26316592
    2. CPMG RD data analysis thus allowed a detailed structural characterization of the ADA2h denatured state under folding conditions not previously achieved for this protein. PMID: 26115097
    3. Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2. PMID: 21098023
    4. changes in zinc ligation promote remodeling of the active site in the zinc hydrolase superfamily PMID: 11743734
    5. NMR structure of the activation domain PMID: 12538893
    6. The high-resolution crystal structure and solution NMR structure of AYEdesign show that the experimentally determined backbone and side-chains conformations are effectively superimposable with the computational model at atomic resolution. PMID: 17196978
    7. we have used one of the best-characterized models for folding and misfolding, the activation domain of procarboxypeptidase A2. The wild type (WT) and three mutants affecting the kinetics of aggregation have been studied by IR from the folded state PMID: 19817500

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Peptidase M14 family
  • 数据库链接：

    HGNC: 2297

    OMIM: 600688

    KEGG: hsa:1358

    STRING: 9606.ENSP00000222481

    UniGene: Hs.490038