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COX19 Antibody

  • 货号：
    CSB-PA586799
  • 规格：
    ￥1100
  • 图片：
    • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA586799(COX19 Antibody) at dilution 1/50. (Original magnification: ×200)
    • The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA586799(COX19 Antibody) at dilution 1/50. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q49B96
  • 基因名：
    COX19
  • 别名：
    COX19Cytochrome c oxidase assembly protein COX19 antibody; hCOX19 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human COX19
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:10000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis. May be required for the assembly of mitochondrial cytochrome c oxidase.
  • 基因功能参考文献：
    1. COX19 is necessary for the transduction of a SCO1-dependent mitochondrial redox signal that regulates ATP7A-mediated cellular copper efflux. PMID: 23345593
    2. Both hCox18p and hCox19p present significant amino acid identity with the corresponding yeast polypeptides and reveal highly conserved functional domains. PMID: 16212937
  • 亚细胞定位：
    Cytoplasm, cytosol. Mitochondrion intermembrane space. Mitochondrion.
  • 蛋白家族：
    COX19 family
  • 组织特异性：
    Ubiquitously expressed. Highly expressed in skeletal muscle.
  • 数据库链接：

    HGNC: 28074

    OMIM: 610429

    KEGG: hsa:90639

    STRING: 9606.ENSP00000342015

    UniGene: Hs.121593