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COQ5 Antibody

  • 中文名称：
    COQ5兔多克隆抗体
  • 货号：
    CSB-PA005804GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q5HYK3
  • 基因名：
    COQ5
  • 别名：
    COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase antibody; mitochondrial antibody; EC 2.1.1.201 antibody; Ubiquinone biosynthesis methyltransferase COQ5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human COQ5
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
  • 基因功能参考文献：
    1. This is the first report of primary CoQ10 deficiency caused by loss of function of COQ5, with delineation of the clinical, laboratory, histological, and molecular features, and insights regarding targeted treatment with CoQ10 supplementation. PMID: 29044765
    2. The expression of COQ5 was increased. PMID: 27155576
    3. The results that knockdown of the COQ5 gene reduced CoQ10 levels further indicated the critical role of COQ5 in the biosynthesis of CoQ10. PMID: 23354120
  • 亚细胞定位：
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, MenG/UbiE family
  • 组织特异性：
    Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle.
  • 数据库链接：

    HGNC: 28722

    OMIM: 616359

    KEGG: hsa:84274

    STRING: 9606.ENSP00000288532

    UniGene: Hs.17250