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COG8 Antibody

  • 货号：
    CSB-PA846673LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA846673LA01HU diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) COG8 Polyclonal antibody
  • Uniprot No.：
    Q96MW5
  • 基因名：
    COG8
  • 别名：
    COG8 antibody; Conserved oligomeric Golgi complex subunit 8 antibody; COG complex subunit 8 antibody; Component of oligomeric Golgi complex 8 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Conserved oligomeric Golgi complex subunit 8 protein (521-612AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，COG8 Antibody (CSB-PA846673LA01HU)，的标记方式是Non-conjugated。对于COG8 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA846673LB01HU COG8 Antibody, HRP conjugated ELISA
    FITC CSB-PA846673LC01HU COG8 Antibody, FITC conjugated
    Biotin CSB-PA846673LD01HU COG8 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for normal Golgi function.
  • 基因功能参考文献：
    1. The exome sequencing was performed to screen all CDG type II-related genes, and two novel frameshift mutations were found: c.171dupG (p.Leu58Alafs*29) and c.1656dupC (p.Ala553Argfs*15) in COG8. PMID: 28619360
    2. TMED6-COG8 chimera might act as a novel diagnostic marker in TFE3 translocation renal cell carcinoma. PMID: 26045774
    3. wthe origin, evolution and preservation of the COG8/PDF same-strand overlap follow similar mechanistic steps as those documented for antisense overlaps where gain and/or loss of splice sites and polyadenylation signals seems to drive the process. PMID: 21805148
  • 相关疾病：
    Congenital disorder of glycosylation 2H (CDG2H)
  • 亚细胞定位：
    Golgi apparatus membrane; Peripheral membrane protein.
  • 蛋白家族：
    COG8 family
  • 数据库链接：

    HGNC: 18623

    OMIM: 606979

    KEGG: hsa:84342

    STRING: 9606.ENSP00000305459

    UniGene: Hs.130849