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CNOT10 Antibody

  • 货号：
    CSB-PA884495LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA884495LA01HU diluted at 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CNOT10 Polyclonal antibody
  • Uniprot No.：
    Q9H9A5
  • 基因名：
    CNOT10
  • 别名：
    CNOT10CCR4-NOT transcription complex subunit 10 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human CCR4-NOT transcription complex subunit 10 protein (595-744AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CNOT10 Antibody (CSB-PA884495LA01HU)，的标记方式是Non-conjugated。对于CNOT10 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA884495LB01HU CNOT10 Antibody, HRP conjugated ELISA
    FITC CSB-PA884495LC01HU CNOT10 Antibody, FITC conjugated
    Biotin CSB-PA884495LD01HU CNOT10 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex.
  • 基因功能参考文献：
    1. Human CNOT10 and CNOT11 form a complex that interacts with the CNOT1 N-terminal domain. PMID: 23303381
    2. CNOT11 interacts with the first amino acids of CNOT1 and with CNOT10 and is required for the association of CNOT10 with the CCR4-NOT complex. PMID: 23232451
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    CNOT10 family
  • 数据库链接：

    HGNC: 23817

    KEGG: hsa:25904

    STRING: 9606.ENSP00000330060

    UniGene: Hs.444851