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CNN3 Antibody

  • 货号：
    CSB-PA005657LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA005657LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA005657LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA005657LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: Mouse liver tissue
      All lanes: CNN3 antibody at 3.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 37, 32 kDa
      Observed band size: 37 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CNN3 Polyclonal antibody
  • Uniprot No.：
    Q15417
  • 基因名：
    CNN3
  • 别名：
    Acidic calponin 3 antibody; acidic isoform antibody; Calponin 3 acidic antibody; Calponin 3 antibody; Calponin acidic antibody; Calponin acidic isoform antibody; Calponin antibody; Calponin-3 antibody; Calponin3 antibody; CNN 3 antibody; Cnn3 antibody; CNN3_HUMAN antibody; dJ639P13.2.2 antibody; OTTHUMP00000012470 antibody; OTTHUMP00000012471 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Calponin-3 protein (2-329AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CNN3 Antibody (CSB-PA005657LA01HU)，的标记方式是Non-conjugated。对于CNN3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005657LB01HU CNN3 Antibody, HRP conjugated ELISA
    FITC CSB-PA005657LC01HU CNN3 Antibody, FITC conjugated
    Biotin CSB-PA005657LD01HU CNN3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
  • 基因功能参考文献：
    1. These results reveal the importance of the MEKK1-calponin-3 signaling pathway to cell contractility. PMID: 27528401
    2. overexpressed CNN3 during sonic vibration increases expression of glutamate receptors and promotes functional neural differentiation of human umbilical cords-mesenchymal stem cells. PMID: 26175098
    3. CNN3 as a new pro-invasive protein in trophoblast cells that is induced under low oxygen conditions. PMID: 25050546
    4. Participates in actin stress fiber remodeling PMID: 23545751
    5. The mRNA and protein level of calponin-3 were increase expression in brain in patiens with epilepsy. PMID: 22119193
    6. Results indicate that CNN3 regulates actin cytoskeleton rearrangement which is required for the plasma membranes of trophoblasts to become fusion competent. PMID: 20861310
    7. These results suggest a role of calponin 3 in the regulation of Bone morphogenetic proteins -dependent cellular responses. PMID: 17825283
    8. Gene rearrangements of CNN3 is associated with mucosa-associated lymphoid tissue lymphoma. PMID: 18927281

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  • 蛋白家族：
    Calponin family
  • 组织特异性：
    Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.
  • 数据库链接：

    HGNC: 2157

    OMIM: 602374

    KEGG: hsa:1266

    STRING: 9606.ENSP00000359225

    UniGene: Hs.483454