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CINP Antibody

  • 货号：
    CSB-PA861151LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CINP Polyclonal antibody
  • Uniprot No.：
    Q9BW66
  • 基因名：
    CINP
  • 别名：
    CDK2-interacting protein antibody; CINP antibody; CINP protein antibody; CINP_HUMAN antibody; Cyclin dependent kinase 2 interacting protein antibody; Cyclin-dependent kinase 2-interacting protein antibody; MGC849 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Cyclin-dependent kinase 2-interacting protein (1-212AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CINP Antibody (CSB-PA861151LA01HU)，的标记方式是Non-conjugated。对于CINP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA861151LB01HU CINP Antibody, HRP conjugated ELISA
    FITC CSB-PA861151LC01HU CINP Antibody, FITC conjugated
    Biotin CSB-PA861151LD01HU CINP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Interacts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
  • 基因功能参考文献：
    1. NS5B delays cells in S phase through interaction with CINP and relocalization of the protein from the nucleus to the cytoplasm PMID: 21628470
    2. CINP is part of the Cdc7-dependent mechanism of origin firing and a functional and physical link between Cdk2 and Cdc7 complexes at the origins PMID: 16082200
    3. CINP interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress, and G2 checkpoint integrity. PMID: 19889979
  • 亚细胞定位：
    Nucleus. Note=Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
  • 蛋白家族：
    CINP family
  • 数据库链接：

    HGNC: 23789

    OMIM: 613362

    KEGG: hsa:51550

    STRING: 9606.ENSP00000442057

    UniGene: Hs.129634