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CHODL Antibody

  • 货号：
    CSB-PA005370LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate
      All lanes: CHODL antibody at 6.2µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31, 26, 28, 29 kDa
      Observed band size: 31 kDa
    • IHC image of CSB-PA005370LA01HU diluted at 1:300 and staining in paraffin-embedded human spleen tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA005370LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CHODL Polyclonal antibody
  • Uniprot No.：
    Q9H9P2
  • 基因名：
    CHODL
  • 别名：
    C21orf68 antibody; Chodl antibody; CHODL_HUMAN antibody; Chondrolectin antibody; Chromosome 21 open reading frame 68 antibody; FLJ12627 antibody; MT75 antibody; PRED12 antibody; Transmembrane protein MT75 antibody; UNQ872/PRO1890 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Chondrolectin protein (105-206AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CHODL Antibody (CSB-PA005370LA01HU)，的标记方式是Non-conjugated。对于CHODL Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005370LB01HU CHODL Antibody, HRP conjugated ELISA
    FITC CSB-PA005370LC01HU CHODL Antibody, FITC conjugated
    Biotin CSB-PA005370LD01HU CHODL Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance.
  • 基因功能参考文献：
    1. Data indicate that chondrolectin (CHODL) is likely to be a prognostic biomarker in the clinic and targeting CHODL might be a strategy for the development of anticancer drugs. PMID: 22016508
    2. cloning and characterization; localized at chromosome 21q21 PMID: 12079284
    3. study describes the molecular characterization of novel members of the chondrolectin family associated with T cell maturation and a subcellular localization of chondrolectin f isoform in the endoplasmic reticulum-Golgi apparatus PMID: 12621022
    4. CHODLDeltaE/CHODLfDeltaE protein variant localizes in the late endoplasmic reticulum and is detected in spleen and tonsils; the isoform seems to be differentially expressed in thymocytes and lymphocytes. PMID: 17606388
  • 亚细胞定位：
    Cytoplasm. Membrane; Single-pass type I membrane protein.; [Isoform 2]: Endoplasmic reticulum. Endoplasmic reticulum membrane; Single-pass type I membrane protein.; [Isoform 3]: Cytoplasm.
  • 组织特异性：
    Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. B lymphocytes express isoform 2 only; p
  • 数据库链接：

    HGNC: 17807

    OMIM: 607247

    KEGG: hsa:140578

    STRING: 9606.ENSP00000299295

    UniGene: Hs.283725