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CHML Antibody

  • 货号：
    CSB-PA003958
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using REP-2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P26374
  • 基因名：
    CHML
  • 别名：
    CHM like antibody; Chml antibody; Choroideraemia like protein antibody; Choroideraemia-like protein antibody; Choroideremia like (Rab escort protein 2) antibody; Choroideremia like antibody; Choroideremia like protein antibody; Rab escort protein 2 antibody; Rab proteins geranylgeranyltransferase component A 2 antibody; RAE2_HUMAN antibody; REP 2 antibody; REP-2 antibody; REP2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human REP-2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
  • 基因功能参考文献：
    1. Polymorphisms in the OPN3 and CHML genes are associated with asthma and atopic asthma. PMID: 18344558
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Rab GDI family
  • 数据库链接：

    HGNC: 1941

    OMIM: 118825

    KEGG: hsa:1122

    STRING: 9606.ENSP00000355511

    UniGene: Hs.654545