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CELF6 Antibody

  • 货号：
    CSB-PA002825GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96J87
  • 基因名：
    CELF6
  • 别名：
    6330569O16Rik antibody; Bruno like 6; RNA binding protein (Drosophila) antibody; bruno like 6; RNA binding protein antibody; Bruno like protein 6 antibody; Bruno-like protein 6 antibody; BRUNOL6 antibody; CELF-6 antibody; Celf6 antibody; CELF6_HUMAN antibody; CUG-BP- and ETR-3-like factor 6 antibody; CUGBP and ETR3 like factor 6 antibody; CUGBP Elav-like family member 6 antibody; RNA binding protein BRUNOL 6 antibody; RNA-binding protein BRUNOL-6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human BRUNOL6
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
  • 基因功能参考文献：
    1. Analysis of common variants near the corresponding genes implicated the RNA binding protein CELF6 in autism risk PMID: 23407934
    2. CELF6 is a member of the CELF family of RNA-binding proteins that regulates muscle-specific splicing enhancer-dependent alternative splicing PMID: 14761971
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    CELF/BRUNOL family
  • 组织特异性：
    Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney.
  • 数据库链接：

    HGNC: 14059

    OMIM: 612681

    KEGG: hsa:60677

    STRING: 9606.ENSP00000287202

    UniGene: Hs.348342