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CDK18 Antibody

  • 货号：
    CSB-PA017650GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q07002
  • 基因名：
    CDK18
  • 别名：
    Cdk18 antibody; CDK18_HUMAN antibody; Cell division protein kinase 18 antibody; Cyclin-dependent kinase 18 antibody; PCTAIRE 3 antibody; PCTAIRE antibody; PCTAIRE motif protein kinase 3 antibody; PCTAIRE protein kinase 3 antibody; PCTAIRE-motif protein kinase 3 antibody; PCTK 3 antibody; Serine/threonine-protein kinase PCTAIRE-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PCTK3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in signal transduction cascades in terminally differentiated cells.
  • 基因功能参考文献：
    1. these data reveal a rate-limiting role for CDK18 in replication stress signalling and establish it as a novel regulator of genome integrity. PMID: 27382066
    2. Increased levels of PCTAIRE3 is associated with Alzheimer's disease. PMID: 26885753
    3. Expression of PCTAIRE 3a (474 amino acids) was evident throughout the brain and in the majority of tissues analyzed, while spliced isoform PCTAIRE 3b (504 amino acids) was limited to several subcortical nuclei of the basal gangli and the spinal cord. PMID: 15019984
    4. PCTAIRE 3 is aassociated kinase that modulates tau phosphorylation in Alzeheimer's disease. PMID: 16766195
  • 蛋白家族：
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
  • 组织特异性：
    Isoform 2 expression is limited to several subcortical nuclei of the basal gangli and the spinal cord. Isoform 1 is widely expressed.
  • 数据库链接：

    HGNC: 8751

    OMIM: 169190

    KEGG: hsa:5129

    UniGene: Hs.445402