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CDH16 Antibody

  • 货号：
    CSB-PA001148
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of A549 cells using Cadherin-16 Polyclonal Antibody
    • Western Blot analysis of HuvEc cells using Cadherin-16 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O75309
  • 基因名：
    CDH16
  • 别名：
    CAD16_HUMAN antibody; Cadherin 16 antibody; Cadherin 16 KSP cadherin antibody; Cadherin kidney antibody; Cadherin-16 antibody; CDH 16 antibody; CDH16 antibody; Kidney cadherin antibody; Kidney specific cadherin antibody; Kidney-specific cadherin antibody; Ksp cadherin antibody; Ksp-cadherin antibody; PRO1340 antibody; UNQ695 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Cadherin-16.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • 基因功能参考文献：
    1. Our study expands the clinical and allelic spectrum of known Retinal dystrophies genes, and reveals AGBL5, CDH16, and DNAJC17 as novel disease candidates. PMID: 26355662
    2. In thyroid carcinomas, as determined by quantitative RT-PCR, CDH16 expression decreases in papillary, follicular, and anaplastic thyroid carcinomas, and the decrease is more pronounced than that of CDH1. PMID: 22028439
    3. These results indicated that LIF induced multi-lineage differentiation of adult stem-like cells in kidney via cadherin 16. PMID: 15670782
    4. Ksp-cadherin expression downregulated inrenal cell carcinoma; this cell adhesion molecule may have role in tumour suppression PMID: 15886705
    5. Ksp-cad is a useful tumor type associated marker for distinguishing chromophobe renal cell carcinoma and renal oncocytoma from the wide range of nonintercalated cell-related adult renal epithelial neoplasms. PMID: 17895753
    6. The interaction of Ksp-cadherin with alpha B-crystallin is important for the connection of Ksp-cadherin to the cytoskeleton and thus for maintaining tissue integrity in the kidney. PMID: 18343407

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Kidney specific.
  • 数据库链接：

    HGNC: 1755

    OMIM: 603118

    KEGG: hsa:1014

    STRING: 9606.ENSP00000299752

    UniGene: Hs.513660