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CDC123 Antibody

  • 货号：
    CSB-PA004984LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA004984LA01HU diluted at 1:500 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CDC123 Polyclonal antibody
  • Uniprot No.：
    O75794
  • 基因名：
  • 别名：
    C10orf7 antibody; CD123_HUMAN antibody; CDC123 antibody; Cell division cycle 123 antibody; Cell division cycle 123 homolog antibody; Cell division cycle protein 123 homolog antibody; D123 antibody; HT 1080 antibody; HT-1080 antibody; Protein D123 antibody; PZ32 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Cell division cycle protein 123 homolog protein (44-97AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CDC123 Antibody (CSB-PA004984LA01HU)，的标记方式是Non-conjugated。对于CDC123 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA004984LB01HU CDC123 Antibody, HRP conjugated ELISA
    FITC CSB-PA004984LC01HU CDC123 Antibody, FITC conjugated
    Biotin CSB-PA004984LD01HU CDC123 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for S phase entry of the cell cycle.
  • 基因功能参考文献：
    1. There were no statistically significant differences in the distribution of CDC123/CAMK1D rs12779790 genotypes and alleles between women with gestational diabetes mellitus and healthy pregnant women. PMID: 28079868
    2. CDC123 may have a role in novel protein modifications PMID: 25976611
    3. Association to type 2 diabetes was found for rs13266634 (SLC30A8), rs7923837 (HHEX), rs10811661 (CDKN2A/2B), rs4402960 (IGF2BP2), rs12779790 (CDC123/CAMK1D), and rs2237892 (KCNQ1). PMID: 22923468
    4. A significant association of rs10906115 in CDC123/CAMK1D and rs1359790 near SPRY2 was identified with type 2 diabetes in a Japanese population. PMID: 21909839
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    CDC123 family
  • 组织特异性：
    Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.
  • 数据库链接：

    HGNC: 16827

    OMIM: 617708

    KEGG: hsa:8872

    STRING: 9606.ENSP00000281141

    UniGene: Hs.412842