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CD300LB Antibody

  • 货号：
    CSB-PA004919LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CD300LB Polyclonal antibody
  • Uniprot No.：
    A8K4G0
  • 基因名：
    CD300LB
  • 别名：
    CD300LB antibody; CD300B antibody; CLM7 antibody; CMRF35A2 antibody; IREM3 antibody; LMIR5 antibody; TREM5 antibody; UNQ2530/PRO6029CMRF35-like molecule 7 antibody; CLM-7 antibody; CD300 antigen-like family member B antibody; CMRF35-A2 antibody; Immune receptor expressed on myeloid cells 3 antibody; IREM-3 antibody; Leukocyte mono-Ig-like receptor 5 antibody; Triggering receptor expressed on myeloid cells 5 antibody; TREM-5 antibody; CD antigen CD300b antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human CMRF35-like molecule 7 protein (18-151AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CD300LB Antibody (CSB-PA004919LA01HU)，的标记方式是Non-conjugated。对于CD300LB Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA004919LB01HU CD300LB Antibody, HRP conjugated ELISA
    FITC CSB-PA004919LC01HU CD300LB Antibody, FITC conjugated
    Biotin CSB-PA004919LD01HU CD300LB Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.
  • 基因功能参考文献：
    1. this paper identified CD300b as an lipopolysaccharide-recognizing receptor that regulated TLR4 signaling PMID: 27261276
    2. CD300LB expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    3. CD300 molecules are all expressed by DC; CD300b, d, e and f are restricted to different subpopulations of the myeloid DC lineage. They have been shown to regulate DC function both in vitro and in vivo. PMID: 23072861
    4. CD300b defines a nonclassical Ig receptor able to trigger signals by coupling distinct mediators and thus initiating different signaling pathways PMID: 16920917
    5. although both mouse and human LMIR5 play activatory roles in innate immunity cells, the functions of LMIR5 were differentially regulated in mouse versus human cells. PMID: 17928527

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  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD300 family
  • 组织特异性：
    Expressed exclusively in myeloid lineages.
  • 数据库链接：

    HGNC: 30811

    OMIM: 610705

    KEGG: hsa:124599

    STRING: 9606.ENSP00000376397

    UniGene: Hs.313343