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CCT7 Antibody

  • 货号：
    CSB-PA859112LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, 293 whole cell lysate
      All lanes: CCT7 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 60, 38, 55, 51 kDa
      Observed band size: 60 kDa
    • IHC image of CSB-PA859112LA01HU diluted at 1:100 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of MCF-7 cells with CSB-PA859112LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CCT7 Polyclonal antibody
  • Uniprot No.：
    Q99832
  • 基因名：
    CCT7
  • 别名：
    CCT ETA antibody; CCT-eta antibody; CCT7 antibody; CCTETA antibody; Ccth antibody; Chaperonin containing t complex polypeptide 1 eta subunit antibody; Chaperonin containing TCP1 subunit 7 (eta) antibody; Chaperonin containing TCP1 subunit 7 antibody; HIV 1 Nef interacting protein antibody; HIV-1 Nef-interacting protein antibody; Nip7 1 antibody; T complex protein 1 eta subunit antibody; T-complex protein 1 subunit eta, N-terminally processed antibody; TCP-1-eta antibody; TCP1eta antibody; TCPH_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human T-complex protein 1 subunit eta protein (240-543AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CCT7 Antibody (CSB-PA859112LA01HU)，的标记方式是Non-conjugated。对于CCT7 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA859112LB01HU CCT7 Antibody, HRP conjugated ELISA
    FITC CSB-PA859112LC01HU CCT7 Antibody, FITC conjugated
    Biotin CSB-PA859112LD01HU CCT7 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin.
  • 基因功能参考文献：
    1. the increased expression of CCT-eta appears to be a marker for latent and active Dupuytren's contracture and to be essential for the increased contractility exhibited by these fibroblasts PMID: 23292503
    2. Functional characterization of the CCT complex and its subunits in mouse. PMID: 11532003
    3. A protein in mouse, that is highly similar to the one described in this record, was found to interact with a protein involved in the Nitric oxide (NO) signal transduction pathway, soluble guanylyl cyclase (sGC). PMID: 15347653
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    TCP-1 chaperonin family
  • 数据库链接：

    HGNC: 1622

    OMIM: 605140

    KEGG: hsa:10574

    STRING: 9606.ENSP00000258091

    UniGene: Hs.368149