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CCNL2 Antibody

  • 货号：
    CSB-PA004830GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96S94
  • 基因名：
    CCNL2
  • 别名：
    CCNL2 antibody; SB138Cyclin-L2 antibody; Paneth cell-enhanced expression protein antibody
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human CCNL2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors.
  • 基因功能参考文献：
    1. Therefore, cyclin L2-mediated control of SAMHD1 levels in macrophages supports HIV-1 replication. PMID: 25532805
    2. CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome. PMID: 24218572
    3. characterize cyclin L2 as a highly mobile component of nuclear speckles and suggest that DYRK1A may regulate splicing by phosphorylation of cyclin L2 PMID: 14623875
    4. represents a new member of the cyclin family, which might regulate the transcription and RNA processing of certain apoptosis-related factors PMID: 14684736
  • 亚细胞定位：
    Nucleus speckle. Nucleus, nucleoplasm.
  • 蛋白家族：
    Cyclin family, Cyclin L subfamily
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 20570

    OMIM: 613482

    KEGG: hsa:81669

    STRING: 9606.ENSP00000383611

    UniGene: Hs.515704