CAMSAP2 Antibody
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) CAMSAP2 Polyclonal antibody
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Uniprot No.:Q08AD1
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基因名:CAMSAP2
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别名:CAMSAP2 antibody; CAMSAP1L1 antibody; KIAA1078 antibody; Calmodulin-regulated spectrin-associated protein 2 antibody; Calmodulin-regulated spectrin-associated protein 1-like protein 1 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Calmodulin-regulated spectrin-associated protein 2 protein (1-150AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:Antigen Affinity Purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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产品提供形式:Liquid
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应用范围:ELISA, IHC
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推荐稀释比:
Application Recommended Dilution IHC 1:20-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
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功能:Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and autonomously decorates and stabilizes microtubule lattice formed by microtubule minus-end polymerization. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In addition, it also reduces the velocity of microtubule polymerization. Through the microtubule cytosk...显示更多
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基因功能参考文献:
- The CAMSAP/Nezha/Patronin family protein CAMSAP2 specifically localizes to noncentrosomal microtubule minus-ends and is required for proper microtubule organization in neurons. PMID: 24908486
- These results show that members of the CAMSAP/Patronin family all localize to and protect minus-ends but have evolved distinct effects on microtubule dynamics. PMID: 24706919
- the rs2292096 G allele of CAMSAP1L1, which was associated with reduced risk of symptomatic epilepsy, tended to associate with increased expression of CAMSAP1L1, which represses neurite outgrowth. PMID: 24148305
- in a two-stage GWAS to identify common susceptibility variants of epilepsy in Chinese, the strongest signals were observed with two highly correlated variants, rs2292096 and rs6660197, with the former reaching genome-wide significance, on 1q32.1 in the CAMSAP1L gene PMID: 22116939
- The CKK domain binds microtubules and represents a domain that evolved with the metazoa. PMID: 19508979
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相关疾病:Defects in CAMSAP2 may be a cause of susceptibility to epilepsy in the Chinese population.
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亚细胞定位:Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm.
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蛋白家族:CAMSAP1 family
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数据库链接:
HGNC: 29188
OMIM: 613775
KEGG: hsa:23271
UniGene: Hs.23585