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CALHM3 Antibody

  • 货号：
    CSB-PA768231LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      All lanes: CALHM3 antibody at 8µg/ml + Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 40, 39 kDa
      Observed band size: 40, 55 kDa
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA768231LA01HU at dilution of 1:100
    • Immunofluorescent analysis of U251 cells using CSB-PA768231LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CALHM3 Polyclonal antibody
  • Uniprot No.：
    Q86XJ0
  • 基因名：
    CALHM3
  • 别名：
    CALHM3; FAM26A; Calcium homeostasis modulator protein 3; Protein A
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Calcium homeostasis modulator protein 3 protein (201-350AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CALHM3 Antibody (CSB-PA768231LA01HU)，的标记方式是Non-conjugated。对于CALHM3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA768231LB01HU CALHM3 Antibody, HRP conjugated ELISA
    FITC CSB-PA768231LC01HU CALHM3 Antibody, FITC conjugated
    Biotin CSB-PA768231LD01HU CALHM3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
  • 基因功能参考文献：
    1. This study failed to show an association between theeight SNPs of the CALHM3 genes and alzheimer disease. PMID: 20164573
  • 亚细胞定位：
    Basolateral cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    CALHM family
  • 组织特异性：
    Specifically expressed in circumvallate taste bud cells.
  • 数据库链接：

    HGNC: 23458

    KEGG: hsa:119395

    STRING: 9606.ENSP00000358798

    UniGene: Hs.364624