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CACNB3 Antibody

  • 货号：
    CSB-PA080192
  • 规格：
    ￥880
  • 图片：
    • Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using CACNB3 Polyclonal Antibody.
    • Western blot analysis of 1) Mouse Brain Tissue, 2) Rat Brain Tissue using CACNB3 Polyclonal Antibody.
  • 其他：

产品详情

  • Uniprot No.：
    P54284
  • 基因名：
  • 别名：
    CAB3 antibody; CACB3_HUMAN antibody; Cacnb3 antibody; CACNLB3 antibody; Calcium channel voltage dependent beta 3 subunit antibody; Calcium channel voltage-dependent subunit beta 3 antibody; FLJ58949 antibody; Voltage-dependent L-type calcium channel subunit beta-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse,Rat
  • 免疫原：
    Synthetic Peptide
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1000
    IHC 1:200-500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.
  • 基因功能参考文献：
    1. in the presence of Pax6(S), beta(3) is translocated from the cytoplasm to the nucleus;full-length Ca(v)beta may act directly as a transcription regulator independent of its role in regulating Ca(2+) channel activity PMID: 19917615
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Calcium channel beta subunit family
  • 组织特异性：
    Expressed mostly in brain, colon and ovary.
  • 数据库链接：

    HGNC: 1403

    OMIM: 601958

    KEGG: hsa:784

    STRING: 9606.ENSP00000301050

    UniGene: Hs.250712