CA1 Antibody
-
货号:CSB-PA004364ESR2HU
-
规格:¥440
-
促销:
-
图片:
-
其他:
产品详情
-
产品名称:Rabbit anti-Homo sapiens (Human) CA1 Polyclonal antibody
-
Uniprot No.:P00915
-
基因名:
-
别名:CA 1 antibody; CA I antibody; CA-I antibody; CA1 antibody; CAB antibody; CAH1_HUMAN antibody; CAI antibody; CAN antibody; Car 1 antibody; Car1 antibody; Carbonate dehydratase I antibody; Carbonic anhydrase 1 antibody; Carbonic anhydrase A antibody; Carbonic anhydrase B antibody; Carbonic anhydrase B; formerly antibody; Carbonic anhydrase I antibody; Carbonic dehydratase antibody; ECK0125 antibody; JW0122 antibody; yadF antibody
-
宿主:Rabbit
-
反应种属:Human
-
免疫原:Recombinant Human Carbonic anhydrase 1 protein (1-261AA)
-
免疫原种属:Homo sapiens (Human)
-
标记方式:Non-conjugated
-
克隆类型:Polyclonal
-
抗体亚型:IgG
-
纯化方式:Antigen Affinity Purified
-
浓度:It differs from different batches. Please contact us to confirm it.
-
保存缓冲液:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
产品提供形式:Liquid
-
应用范围:ELISA, IHC
-
推荐稀释比:
Application Recommended Dilution IHC 1:20-1:200 -
Protocols:
-
储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
-
功能:Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
-
基因功能参考文献:
- Anti-CA I and II antibody levels were investigated using ELISA in serum samples from 30 patients with Acute Myeloid Leukemia (AML) and 30 healthy peers. Anti-CA I and II antibody titers in the AML group were significantly higher compared with the control group (p=0.0001 and 0.018, respectively). PMID: 28270370
- These six-membered carbocycles showed nice inhibitory action against AChE and human carbonic anhydrase (hCA) II and I isoforms. The hCA I, II, and AChE were efficiently inhibited by these molecules, with Ki values in the range of 6.70-35.85 nM for hCA I, 18.77-60.84 nM for hCA II, and 0.74-4.60 for AChE, respectively PMID: 28613396
- These results showed that flavonoids especially malvin and oenin effectively inhibited hCA I and II isoenzymes. PMID: 28445001
- Discovery of potent carbonic anhydrase, acetylcholinesterase, and butyrylcholinesterase enzymes inhibitors: The new amides and thiazolidine-4-ones synthesized on an acetophenone base. PMID: 28544359
- Here are presented solved the first crystal structures of carbonic anhydrase 1and carbonic anhydrase 2 in complex with polmacoxib, at 2.0 A and 1.8 A, respectively. PMID: 27475498
- Neuronal carbonic anhydrase I (CA1) appears to be associated with the endoplasmic reticulum subcellular structure. PMID: 27809276
- CA1 is highly expressed in the sera of stage I non-small cell lung cancer patients PMID: 26232327
- We demonstrated that resveratrol, caffeic acid, and tannic acid in stored blood could decrease the sensitivity to oxidation of erythrocytes in vitro but did not exhibit such effects on Carbonic Anhydrase activity. PMID: 27413740
- CA1 is a potential oncogene and that it contributes to abnormal cell calcification, apoptosis and migration in breast cancer. PMID: 26459317
- We report on the competitive zinc metalation of apo-carbonic anhydrase [CA; metal-free CA (apo-CA)] in the presence of apo-metallothionein 1A domain fragments to identify domain specific determinants of zinc binding and zinc donation PMID: 26475450
- The gene encoding CA1 is susceptible to ankylosing spondylitis and plays a role in the process of bone formation. PMID: 22838845
- Structure-activity relationships study showed that indolylchalcone derivatives have higher inhibitory activities than pyrido[2,3-d]pyrimidine derivatives on hCA I and hCA II. PMID: 25165709
- Myocardial carbonic anhydrase 1/2 activation is significantly elevated in diabetic ischemic cardiomyopathy. PMID: 24670789
- may be involved in the pathogenesis of Abdominal aortic aneurysm PMID: 23557951
- The new prognostic biomarkers GRP78, Fructose-bisphosphate Aldolase A (ALDOA), Carbonic Anhydrase I (CA1) and Peptidyl-prolyl cis-trans isomerase A or Cyclophilin A (PPIA)) provided good survival prediction for TNM stage I-IV patients. PMID: 22996014
- A significant correlation was found between positive carbonic anhydrase I staining and oral squamous cell carcinoma for more advanced clinical stage and larger tumor size, but not for positive lymph node metastasis, distal metastasis, and recurrence. PMID: 22416960
- carbonic anhydrase I, phosphoglycerate kinase 1 and apolipoprotein A-I appeared to be the most significant variations of proteins in patients with osteopenia and osteoarthritis PMID: 22619369
- A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. PMID: 22360420
- Overexpression of CA1 in the synovial tissues of ankylosing spondylitis (AS) patients may promote improper calcification and bone resorption in AS. PMID: 21143847
- single mutation of an amino acid not considered essential to catalysis (Phe91Asn) in carbonic anhydrase I, but is near substrate binding pocket, led to increase of catalytic activity; mutant CA I also showed higher affinity for sulfonamide inhibitors PMID: 20624682
- The X-ray crystallographic structure of the CA I Michigan 1 variant isozyme is reported, both in the presence and absence of a second bound zinc ion coordinated to His 64, His 200, and Arg 67. PMID: 12009884
- concentrations in nondialyzed chronic kidney disease patients, and the relationship with acidosis, zinc, anemia, and iron supplementation PMID: 14675565
- cytosolic CA I, II, and XIII are downregulated in neoplastic colorectal mucosa compared to normal colorectal mucosa PMID: 15836783
- Isothiocyanato sulfonamide thioureas inhibit this enzyme. PMID: 15837325
- X-ray crystallographic structure for the adduct of an activator with hCA I. Binding site interactions of activator L-Histidine with active site amino acids PMID: 16870440
- study presents the X-ray structure of the foscarnet adduct with CA1 together with the factors governing recognition of such small molecules by a metalloenzyme active site PMID: 17314045
- Decreased levels of carbonic anhydrase 1 isozyme is associated with type II diabetes. PMID: 17464559
显示更多
收起更多
-
亚细胞定位:Cytoplasm.
-
蛋白家族:Alpha-carbonic anhydrase family
-
数据库链接:
HGNC: 1368
OMIM: 114800
KEGG: hsa:759
STRING: 9606.ENSP00000256119
UniGene: Hs.23118
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-