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C16orf62 Antibody

  • 货号：
    CSB-PA773584HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of HepG2 cells using CSB-PA773584HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, Hela whole cell lysate
      All lanes: C16orf62 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 110, 94 kDa
      Observed band size: 110 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) C16orf62 Polyclonal antibody
  • Uniprot No.：
    Q7Z3J2
  • 基因名：
    C16orf62
  • 别名：
    C16orf62 antibody; Chromosome 16 open reading frame 62 antibody; CP062_HUMAN antibody; DKFZp313M0539 antibody; DKFZp434B0212 antibody; Esophageal cancer associated protein antibody; Esophageal cancer-associated protein antibody; FLJ21040, antibody; Hypothetical protein LOC57020 antibody; MGC16824 antibody; UPF0505 protein C16orf62 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human UPF0505 protein C16orf62 protein (6-205AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，C16orf62 Antibody (CSB-PA773584HA01HU)，的标记方式是Non-conjugated。对于C16orf62 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA773584HB01HU C16orf62 Antibody, HRP conjugated ELISA
    FITC CSB-PA773584HC01HU C16orf62 Antibody, FITC conjugated
    Biotin CSB-PA773584HD01HU C16orf62 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as component of the retriever complex. The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes. In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association with the CCC complex and cooperation with the WASH complex on early endosomes. Seems not to be required for CCC complex stability.; (Microbial infection) The heterotrimeric retriever complex, in collaboration with the CCC complex, mediates the exit of human papillomavirus to the cell surface.
  • 基因功能参考文献：
    1. Heterotrimer composed of DSCR3, C16orf62 and VPS29 orchestrates endosomal cargo retrieval and recycling. PMID: 28892079
  • 亚细胞定位：
    Membrane; Single-pass membrane protein. Endosome.
  • 蛋白家族：
    UPF0505 family
  • 数据库链接：

    HGNC: 24641

    KEGG: hsa:57020

    STRING: 9606.ENSP00000400815

    UniGene: Hs.654964