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BTG4 Antibody

  • 货号：
    CSB-PA002866GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NY30
  • 基因名：
    BTG4
  • 别名：
    B cell translocation gene 4 antibody; BTG family member 4 antibody; Btg4 antibody; BTG4_HUMAN antibody; MGC33003 antibody; PC3B antibody; Protein BTG4 antibody; Protein PC3b antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human BTG4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E. Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development.
  • 基因功能参考文献：
    1. BTG4 could contribute to chronic lymphocytic leykemia pathogenesis following inactivation by haploinsufficiency. PMID: 15672409
    2. miR-34b/c and BTG4 are novel tumor suppressors in colorectal cancer (CRC) and that the miR-34b/c CpG island, which bidirectionally regulates miR-34b/c and BTG4, is a frequent target of epigenetic silencing in CRC PMID: 18519671
    3. these data support BTG4 as a candidate tumor suppressor gene that is epigenetically silenced in the majority of gastric cancers. PMID: 19576178
  • 蛋白家族：
    BTG family
  • 组织特异性：
    Expressed in oocytes after germinal vesicle breakdown. Expressed in testis and in olfactory epithelium.
  • 数据库链接：

    HGNC: 13862

    OMIM: 605673

    KEGG: hsa:54766

    STRING: 9606.ENSP00000348300

    UniGene: Hs.128180