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BRI3BP Antibody

  • 货号：
    CSB-PA990945
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from RAW264.7 cells, using BRI3B antibody.
    • Immunohistochemistry analysis of paraffin-embedded human brain tissue using BRI3B antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) BRI3BP Polyclonal antibody
  • Uniprot No.：
    Q8WY22
  • 基因名：
    BRI3BP
  • 别名：
    BRI3BP; KG19; BRI3-binding protein; I3-binding protein; Cervical cancer 1 proto-oncogene-binding protein KG19; HCCRBP-1
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human BRI3B.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in tumorigenesis and may function by stabilizing p53/TP53.
  • 基因功能参考文献：
    1. HCCRBP-3 induces tumorigenesis through direct interaction with HCCR-1 in human cancers. PMID: 22851403
    2. highly expressed in brain, kidney, and liver; mapped to human chromosome 12q24.2-qter PMID: 11860200
    3. Taken together, BRI3BP, widely expressed in animal cell types, seems to possess a pro-apoptotic property and can potentiate drug-induced apoptosis. PMID: 17765869
  • 亚细胞定位：
    Mitochondrion outer membrane; Multi-pass membrane protein.
  • 组织特异性：
    Most abundantly expressed in brain, liver and kidney. Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas.
  • 数据库链接：

    HGNC: 14251

    OMIM: 615627

    KEGG: hsa:140707

    STRING: 9606.ENSP00000340761

    UniGene: Hs.596464