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BPGM Antibody

  • 货号：
    CSB-PA002781ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: BPGM antibody at 5.94µg/ml
      Lane 1: Human peripheral blood mononuclear cells
      Lane 2: Mouse liver tissue
      Lane 3: Human placenta tissue
      Lane 4: Hela whole cell lysate
      Lane 5: 293T whole cell lysate
      Lane 6: A549 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 30 kDa
      Observed band size: 30 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA002781ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) BPGM Polyclonal antibody
  • Uniprot No.：
    P07738
  • 基因名：
    BPGM
  • 别名：
    2 antibody; 2,3-bisphosphoglycerate mutase antibody; 2,3-bisphosphoglycerate mutase, erythrocyte antibody; 2,3-bisphosphoglycerate synthase antibody; 2,3-diphosphoglycerate mutase antibody; 3-bisphosphoglycerate mutase antibody; 3-bisphosphoglycerate synthase antibody; 3-diphosphoglycerate mutase antibody; Ab2 098 antibody; AI323730 antibody; AL022789 antibody; Bisphosphoglycerate mutase antibody; BPG dependent PGAM antibody; BPG-dependent PGAM antibody; Bpgm antibody; C86192 antibody; DPGM antibody; Erythrocyte 2,3 bisphosphoglycerate mutase antibody; erythrocyte antibody; PMGE_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Bisphosphoglycerate mutase protein (1-259AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity.
  • 基因功能参考文献：
    1. 1.94 A resolution X-ray structure of bisphosphoglycerate mutase is presented, focusing on the dynamic nature of key ligand-binding residues and their interaction with the inhibitor citrate PMID: 21045285
    2. bisphosphoglycerate mutase crystallographic structure PMID: 15258155
    3. analysis of histidine phosphorylation in human bisphosphoglycerate mutase PMID: 17052986
  • 相关疾病：
    Bisphosphoglycerate mutase deficiency (BPGMD)
  • 蛋白家族：
    Phosphoglycerate mutase family, BPG-dependent PGAM subfamily
  • 组织特异性：
    Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level).
  • 数据库链接：

    HGNC: 1093

    OMIM: 222800

    KEGG: hsa:669

    STRING: 9606.ENSP00000342032

    UniGene: Hs.198365