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BNIPL Antibody

  • 货号：
    CSB-PA002769GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q7Z465
  • 基因名：
    BNIPL
  • 别名：
    BNIPL antibody; Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human BNIPL
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death.
  • 基因功能参考文献：
    1. These results indicate the presence of two BNIP-S splicing variants as cellular regulators and that the BCH domain of BNIP-Salpha confers a novel apoptotic function. The significance of this is discussed PMID: 11741952
    2. interaction with cell proliferation-related proteins, MIF and GFER PMID: 12681488
    3. BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis. PMID: 12901880
    4. Data suggest that Bcl-2/adenovirus E1B 19 ku interacting protein 2-like (BNIPL-2) may regulate apoptosis through changes in the expression of genes associated with cell apoptosis, growth inhibition and cell proliferation. PMID: 15112343
    5. p16INK4, IL-12, TRAIL & lymphotoxin beta gene involved in growth suppression or cell apoptosis were up-regulated & PTEN was down-regulated by BNIPL-1;suggests that it might inhibit cell growth though cell cycle arrest &/or apoptotic cell death pathway(s) PMID: 16143817

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  • 组织特异性：
    Isoform 2 is expressed in placenta and lung.
  • 数据库链接：

    HGNC: 16976

    OMIM: 611275

    KEGG: hsa:149428

    STRING: 9606.ENSP00000357927

    UniGene: Hs.591473