Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. BEST3 Antibody

BEST3 Antibody

  • 货号：
    CSB-PA002668GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8N1M1
  • 基因名：
    BEST3
  • 别名：
    BEST3; VMD2L3; Bestrophin-3; Vitelliform macular dystrophy 2-like protein 3
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Human BEST3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
  • 基因功能参考文献：
    1. results demonstrated that Best-3 is an endogenous inhibitor of NF-kappaB signaling pathway in endothelial cells, suggesting that forced Best-3 expression may be a novel approach for the treatment of vascular inflammatory diseases. PMID: 25329324
    2. These results suggest that an auto-inhibitory mechanism in C termini of bestrophin 3 may be universal among bestrophins investigated in the study. PMID: 17442670
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Bestrophin family
  • 组织特异性：
    Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.
  • 数据库链接：

    HGNC: 17105

    OMIM: 607337

    KEGG: hsa:144453

    STRING: 9606.ENSP00000332413

    UniGene: Hs.280782