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BCL7B Antibody

  • 中文名称：
    BCL7B兔多克隆抗体
  • 货号：
    CSB-PA002628GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BQE9
  • 基因名：
    BCL7B
  • 别名：
    B cell CLL/lymphoma 7 protein family member B antibody; B cell CLL/lymphoma 7B antibody; B-cell CLL/lymphoma 7 protein family member B antibody; BCL 7B antibody; BCL7B antibody; BCL7B_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human BCL7B
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression.
  • 基因功能参考文献：
    1. We herewith propose that the BCL7B gene, located in the chromosomal region commonly deleted in Williams syndrome, could potentially have a role in this particular association. PMID: 27771473
    2. our data indicate that BCL7B/BCL-7 has some roles in maintaining the structure of nuclei and is involved in the modulation of multiple pathways, including Wnt and apoptosis. PMID: 25569233
    3. BCL7B gene deltion is associated with Williams-Beuren Syndrome leading to Burkitt Leukemia. PMID: 23018576
  • 相关疾病：
    BCL7B is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of BCL7B may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • 蛋白家族：
    BCL7 family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 1005

    OMIM: 605846

    KEGG: hsa:9275

    STRING: 9606.ENSP00000223368

    UniGene: Hs.647051