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B3GNT6 Antibody

  • 货号：
    CSB-PA744392LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, HT29 whole cell lysate
      All lanes: B3GNT6 antibody at 10µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 43, 30 kDa
      Observed band size: 43 kDa
    • IHC image of CSB-PA744392LA01HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) B3GNT6 Polyclonal antibody
  • Uniprot No.：
    Q6ZMB0
  • 基因名：
    B3GNT6
  • 别名：
    B3GNT6Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase antibody; EC 2.4.1.147 antibody; Core 3 synthase antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 antibody; BGnT-6 antibody; Beta-1,3-Gn-T6 antibody; Beta-1,3-N-acetylglucosaminyltransferase 6 antibody; Beta3Gn-T6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase protein (251-345AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，B3GNT6 Antibody (CSB-PA744392LA01HU)，的标记方式是Non-conjugated。对于B3GNT6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA744392LB01HU B3GNT6 Antibody, HRP conjugated ELISA
    FITC CSB-PA744392LC01HU B3GNT6 Antibody, FITC conjugated
    Biotin CSB-PA744392LD01HU B3GNT6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
  • 基因功能参考文献：
    1. expression was markedly down-regulated in gastric and colorectal carcinomas PMID: 15755813
    2. alpha2beta1 integrin acquired core3 O-glycans in cells expressing core3 synthase with decreased maturation of beta1 integrin, leading to decreased levels of the alpha2beta1 integrin complex PMID: 19395705
  • 亚细胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 31 family
  • 组织特异性：
    Present in stomach and colon (at protein level). Restricted in the stomach, colon and small intestine, where core 3 structure is present.
  • 数据库链接：

    HGNC: 24141

    OMIM: 615315

    KEGG: hsa:192134

    STRING: 9606.ENSP00000435352

    UniGene: Hs.352622